A very broad, cursory glance at some mounting evidence suggesting widespread autoimmunity which may explain some of the symptoms of Long COVID and adverse reactions seen.
I wrote a literature review last July. I thought it would take a couple of hours. Instead it took days and was extremely concerning. Unfortunately we are starting to see the consequences now.
Be aware this will take years to play out, autoimmunity can have a long latency.
Autoimmune disorders: COVID-19, spike protein & homologous epitopes
I have the same issue with my anthology series. It's easy for me to go down a rabbit hole and there ends up being far too much information to try to examine that it ends up taking days/weeks and I feel burned out at the end.
Thanks for sharing your link! It seems like it may be overwhelmed as I have gotten an error several times, so maybe it's nearing the limit of Substack's capacity?
Substack can feel clunky at times. I noticed that the more figures I include the wonkier it becomes to try and edit my posts. Funnily, I'm actually on a laptop, albeit a cheap one. 🤷♂️
I think it's designed more for email-length, smaller posts so anyone writing several pages worth of content will get slogged down.
I've started writing some reviews as preprints to OSF to sidestep these problems. But it's very time consuming to do properly, so I'm doing a bit of work each week.
I've asked Substack if they can support tables and/or columns as you really need these at times and pasting in as figures isn't ideal. Good thing about Substacks are that, just like here we can comment & interact easily, it's quicker.
Thank you for the very interesting and thorough article. Dr. McMillan has also been beating the drum about autoimmunity issues since the beginning of the pandemic. I think you both are absolutely on the right track.
These COVID-19 researchers have been focused on understanding how the spike protein interacts with the immune system.
Research seems to indicate that exposure to spike protein has a number of long term health consequences that need to be delineated.
Here is a recent paper:
Gerlach, Joachim, et al. "The immune paradox of SARS‐CoV‐2: Lymphocytopenia and autoimmunity evoking features in COVID‐19 and possible treatment modalities." Reviews in Medical Virology (2023): e2423.
In the context of covid vaccine silent organ damage, my research has pointed to low level autoimmunity around ACE-2 and a number of other proteins as the critical target.
Thank you! Although like I said the idea of autoimmunity is not really new as evidence has been around since 2020 so I'm mostly reporting on the information that has come out.
I forgot to mention it in this post, but one thing that's possible is that the virus or its antigens may alter the immune response and so it's possible that the immune response may bias towards autoimmunity. I haven't looked too deeply into this but there's evidence of alterations in the response like a Th2-biased response in the vaccines. This may also be related to the lymphocytopenia being seen as well.
Upon a quick glance I came across this article. It seems to suggest that autoimmunity may be due in part to breakdown of the spike-ACEII complex that may lead to autoreactive epitopes. This would be rather interesting since it's sort of been argued that the thrombocytopenia seen with the adenoviral vector vaccines may be a consequence of the viral vector itself forming a complex with platelet factor 4 and that complex is the one that leads to an autoimmune response.
Thanks for the article. I'll try reading it if I can find the full version online and look at all of the information. The importance if autoimmunity is that it won't hit everyone the same- this is where genetics is a critical component in elucidating these issues but it's again a consequence of not much deeper, comprehensive investigation occurring.
I wrote a literature review last July. I thought it would take a couple of hours. Instead it took days and was extremely concerning. Unfortunately we are starting to see the consequences now.
Be aware this will take years to play out, autoimmunity can have a long latency.
Autoimmune disorders: COVID-19, spike protein & homologous epitopes
https://doorlesscarp953.substack.com/p/autoimmune-disorders-covid-19-spike
I have the same issue with my anthology series. It's easy for me to go down a rabbit hole and there ends up being far too much information to try to examine that it ends up taking days/weeks and I feel burned out at the end.
Thanks for sharing your link! It seems like it may be overwhelmed as I have gotten an error several times, so maybe it's nearing the limit of Substack's capacity?
I experimented with a hyperlinked contents section but it seems to kill some mobiles!
Substack can feel clunky at times. I noticed that the more figures I include the wonkier it becomes to try and edit my posts. Funnily, I'm actually on a laptop, albeit a cheap one. 🤷♂️
I think it's designed more for email-length, smaller posts so anyone writing several pages worth of content will get slogged down.
I've started writing some reviews as preprints to OSF to sidestep these problems. But it's very time consuming to do properly, so I'm doing a bit of work each week.
I've asked Substack if they can support tables and/or columns as you really need these at times and pasting in as figures isn't ideal. Good thing about Substacks are that, just like here we can comment & interact easily, it's quicker.
Thank you for the very interesting and thorough article. Dr. McMillan has also been beating the drum about autoimmunity issues since the beginning of the pandemic. I think you both are absolutely on the right track.
https://philipmcmillan.substack.com/p/health-risks-associated-with-the?
These COVID-19 researchers have been focused on understanding how the spike protein interacts with the immune system.
Research seems to indicate that exposure to spike protein has a number of long term health consequences that need to be delineated.
Here is a recent paper:
Gerlach, Joachim, et al. "The immune paradox of SARS‐CoV‐2: Lymphocytopenia and autoimmunity evoking features in COVID‐19 and possible treatment modalities." Reviews in Medical Virology (2023): e2423.
https://philipmcmillan.substack.com/p/the-silent-covid-vaccine-death?
In the context of covid vaccine silent organ damage, my research has pointed to low level autoimmunity around ACE-2 and a number of other proteins as the critical target.
The standout other protein is neuropilin-1.
Thank you! Although like I said the idea of autoimmunity is not really new as evidence has been around since 2020 so I'm mostly reporting on the information that has come out.
I forgot to mention it in this post, but one thing that's possible is that the virus or its antigens may alter the immune response and so it's possible that the immune response may bias towards autoimmunity. I haven't looked too deeply into this but there's evidence of alterations in the response like a Th2-biased response in the vaccines. This may also be related to the lymphocytopenia being seen as well.
Upon a quick glance I came across this article. It seems to suggest that autoimmunity may be due in part to breakdown of the spike-ACEII complex that may lead to autoreactive epitopes. This would be rather interesting since it's sort of been argued that the thrombocytopenia seen with the adenoviral vector vaccines may be a consequence of the viral vector itself forming a complex with platelet factor 4 and that complex is the one that leads to an autoimmune response.
https://www.frontiersin.org/articles/10.3389/fimmu.2021.582166/full
Thanks for the article. I'll try reading it if I can find the full version online and look at all of the information. The importance if autoimmunity is that it won't hit everyone the same- this is where genetics is a critical component in elucidating these issues but it's again a consequence of not much deeper, comprehensive investigation occurring.