Jun 2, 2023·edited Jun 2, 2023Liked by Modern Discontent
per usual, you're hot on the trail. I've been studying peptides for a bit and am VERY interested in semaglutide (I'm an addiction psychiatrist) because I have some patients who have extreme difficulty stopping drinking (multiple trials of treatments) and they are heavy drinkers.. im going to add, the relationship id like to understand is how GLP-1 may impact the 'compulsion' or 'craving' with food or a substance. People describe to me (who take it for weight loss) a satiety and/or feeling full 'im done'. That is similar to my patients who use naltrexone (in a harm reduction method) and feel one drink is enough.
Given that opioid addiction has been a declared emergency since 2017, Becerra has already laid the groundwork for authorizing such treatments via Emergency Use Authorization.
There is another way. For weight control it involves avoiding foods to which the individual has become sensitized, and ensuring that what remains is of high quality. It's hard to see how experiments on rodents fed the usual crap-in-a-bag diets would ever shed light on any of this, any more than do RCTs employing one pharmaceutical as a "placebo" for comparison with another shed light on efficacy.
For addictions, and for weight control beyond what stems from bad food itself, there are other causes to consider, pharmaceutical consumption insufficiency not being one of them. A book that I read years ago comes to mind, _In the Realm of Hungry Ghosts_ by Gabor Maté and Peter A. Levine (2010). It speaks of the "hole in the soul" underlying addiction.
When dealing with "the diseases of [modern] civilization", the answer is not likely to be drugs. It would more likely -- for those not seeking a quick-and-dirty fix -- look like a return to something resembling what people ate and did before these diseases became epidemic, and what they still eat and do in some "less developed" parts of the world.
per usual, you're hot on the trail. I've been studying peptides for a bit and am VERY interested in semaglutide (I'm an addiction psychiatrist) because I have some patients who have extreme difficulty stopping drinking (multiple trials of treatments) and they are heavy drinkers.. im going to add, the relationship id like to understand is how GLP-1 may impact the 'compulsion' or 'craving' with food or a substance. People describe to me (who take it for weight loss) a satiety and/or feeling full 'im done'. That is similar to my patients who use naltrexone (in a harm reduction method) and feel one drink is enough.
Given that opioid addiction has been a declared emergency since 2017, Becerra has already laid the groundwork for authorizing such treatments via Emergency Use Authorization.
https://newsletter.allfactsmatter.us/p/fda-pulls-pfizer-and-moderna-euas
Which means if Big Pharma thinks it can sell more Ozempic by treating addiction it will get no pushback from the FDA.
There is another way. For weight control it involves avoiding foods to which the individual has become sensitized, and ensuring that what remains is of high quality. It's hard to see how experiments on rodents fed the usual crap-in-a-bag diets would ever shed light on any of this, any more than do RCTs employing one pharmaceutical as a "placebo" for comparison with another shed light on efficacy.
For addictions, and for weight control beyond what stems from bad food itself, there are other causes to consider, pharmaceutical consumption insufficiency not being one of them. A book that I read years ago comes to mind, _In the Realm of Hungry Ghosts_ by Gabor Maté and Peter A. Levine (2010). It speaks of the "hole in the soul" underlying addiction.
When dealing with "the diseases of [modern] civilization", the answer is not likely to be drugs. It would more likely -- for those not seeking a quick-and-dirty fix -- look like a return to something resembling what people ate and did before these diseases became epidemic, and what they still eat and do in some "less developed" parts of the world.
Sounds great. But I thought it had a major side effect of potential bowel cancer?
Idk. I could be wrong.