Apologies for releasing shorter pieces this week. A lot of personal things have arisen this past week and so I haven't been in quite the right mindset, but I do hope to release a multipiece newsletter on Hydroxychloroquine in a few days so please be on the lookout for that!
They've more or less become relative terms, more than anything absolute. I would hope that it ends up not producing possible mutagenic effects, but we may not know for years. Also, if it ends up costing hundreds of dollars I don't see how this can be a viable option for many people.
Agreed, we'll have no clue how safe that stuff is for the quite a few years. There are reasons why it normally takes 5+ years to get a new drug approved, and even then, the FDA still misses things.
As for the cost, in the UK, health care is "free", so it will be their government (NHS) paying for it. I'm not not sure what the situation will be in the US.
Well always remember that nothing in life is free, and if you aren't paying out of pocket they've found another way into your wallet!
It is concerning that other mutagenic drugs have these strong warnings and yet we don't see the same with Molnupiravir. Let's hope we will see something, but it's frustrating that people are treating this as a panacea instead of acting cautiously.
Could you elaborate on the change? The structure of Favipiravir is slightly different than Molnupiravir, although they may have similar mechanisms of action. Are you seeing a lot of use of Molnupiravir in India? It definitely is concerning especially with the possible teratogenicity. It's clearly a drug that has a very questionable safety profile.
I couldn't remember but I looked it up and Favipiravir was developed for influenza and used specifically in Japan. It's mechanism of action is to operate as a mutagen and so it's seeing very limited use (as a heads up, modifications to the nitrogenous base are done with the intent to cause base pair mismatches so any drug with this modification should be assumed to cause that effect). It was a drug Dr. McCollough brought up in his podcast with Joe Rogan and I remember wondering why he was arguing about its use.
Apologies for releasing shorter pieces this week. A lot of personal things have arisen this past week and so I haven't been in quite the right mindset, but I do hope to release a multipiece newsletter on Hydroxychloroquine in a few days so please be on the lookout for that!
"Safe and effective". They keep using that phrase... I don't think it means what they think it means.
They've more or less become relative terms, more than anything absolute. I would hope that it ends up not producing possible mutagenic effects, but we may not know for years. Also, if it ends up costing hundreds of dollars I don't see how this can be a viable option for many people.
Agreed, we'll have no clue how safe that stuff is for the quite a few years. There are reasons why it normally takes 5+ years to get a new drug approved, and even then, the FDA still misses things.
As for the cost, in the UK, health care is "free", so it will be their government (NHS) paying for it. I'm not not sure what the situation will be in the US.
Well always remember that nothing in life is free, and if you aren't paying out of pocket they've found another way into your wallet!
It is concerning that other mutagenic drugs have these strong warnings and yet we don't see the same with Molnupiravir. Let's hope we will see something, but it's frustrating that people are treating this as a panacea instead of acting cautiously.
Could you elaborate on the change? The structure of Favipiravir is slightly different than Molnupiravir, although they may have similar mechanisms of action. Are you seeing a lot of use of Molnupiravir in India? It definitely is concerning especially with the possible teratogenicity. It's clearly a drug that has a very questionable safety profile.
I couldn't remember but I looked it up and Favipiravir was developed for influenza and used specifically in Japan. It's mechanism of action is to operate as a mutagen and so it's seeing very limited use (as a heads up, modifications to the nitrogenous base are done with the intent to cause base pair mismatches so any drug with this modification should be assumed to cause that effect). It was a drug Dr. McCollough brought up in his podcast with Joe Rogan and I remember wondering why he was arguing about its use.