Isn't there some evidence at this point that Sars-Cov2 isn't really a typical upper respiratory tract infection (URTI)? Many ACEII receptors are found in the intestines, as well as in the lungs. This could explain why Quercetin could possibly work better against Covid than standard URTI. I'm neither a doctor nor a chemist, just a curious and avid reader of all things Covid over the past 18 months. Thanks for your work!
Yupp, I think there's good arguments made by doctors that this could be considered a vascular disease. However, one of the arguments that can still be made is that regardless of the symptom presentation the virus infects and spreads in the body the same way. The intestines may indicate the disease progressing further in the body, and so the dynamics at that point are different. There's a lot of stuff at play so it's honestly hard to pin down exactly, although studies looking at Quercetin and maybe things such as IBS or GI issues would be interesting on that front.
My wife and I have been taking quercetin supplement every other since mid 2020. I figure it can't hurt. However, I've been reading the the bio-availability of quercetin in most supplements is quite low?
Late additional reply, but many studies of Quercetin indicate the capsule content (i.e. 500 mg) but will usually include the specific value of Quercetin within each capsule. It may be an issue of manufacturing and finding out the actual amount of Quercetin within each capsule as well as consuming it with a meal, or maybe even with other fruits? It would be interesting to see how much Quercetin is available from eating fruits versus supplementing alone.
Quercetin is apparently fat soluble so it may need to be taken with a meal. However, one of the studies (I can't remember which one) showed that they measured serum levels and it showed a dose-dependent serum concentration. It could also be that many of the compounds found in fruits and vegetables work to help increase the bioavailability, although I'm more speculating in regards to that.
Isn't there some evidence at this point that Sars-Cov2 isn't really a typical upper respiratory tract infection (URTI)? Many ACEII receptors are found in the intestines, as well as in the lungs. This could explain why Quercetin could possibly work better against Covid than standard URTI. I'm neither a doctor nor a chemist, just a curious and avid reader of all things Covid over the past 18 months. Thanks for your work!
Yupp, I think there's good arguments made by doctors that this could be considered a vascular disease. However, one of the arguments that can still be made is that regardless of the symptom presentation the virus infects and spreads in the body the same way. The intestines may indicate the disease progressing further in the body, and so the dynamics at that point are different. There's a lot of stuff at play so it's honestly hard to pin down exactly, although studies looking at Quercetin and maybe things such as IBS or GI issues would be interesting on that front.
My wife and I have been taking quercetin supplement every other since mid 2020. I figure it can't hurt. However, I've been reading the the bio-availability of quercetin in most supplements is quite low?
Late additional reply, but many studies of Quercetin indicate the capsule content (i.e. 500 mg) but will usually include the specific value of Quercetin within each capsule. It may be an issue of manufacturing and finding out the actual amount of Quercetin within each capsule as well as consuming it with a meal, or maybe even with other fruits? It would be interesting to see how much Quercetin is available from eating fruits versus supplementing alone.
Quercetin is apparently fat soluble so it may need to be taken with a meal. However, one of the studies (I can't remember which one) showed that they measured serum levels and it showed a dose-dependent serum concentration. It could also be that many of the compounds found in fruits and vegetables work to help increase the bioavailability, although I'm more speculating in regards to that.