This is a wonderful overview of how mutations arise and the consequences of mutations. The case examples were very interesting and showed how many variants can arise over time even in just one person. I would think a drug such as molnupiravir (nucleoside analog) would be helpful in such cases where current mAB treatments are not effective - especially as a last ditch effort to save lives of older (non-child bearing age) patients. Although data from India for molnupiravir is not looking good for severe disease. So much we don’t know yet…
This is a wonderful overview of how mutations arise and the consequences of mutations. The case examples were very interesting and showed how many variants can arise over time even in just one person. I would think a drug such as molnupiravir (nucleoside analog) would be helpful in such cases where current mAB treatments are not effective - especially as a last ditch effort to save lives of older (non-child bearing age) patients. Although data from India for molnupiravir is not looking good for severe disease. So much we don’t know yet…