Continuing with my series posts here is the one on Hydroxychloroquine.
Part I: History and General Medicinal Properties
To start off, this post gives a good history of Quinine, starting from several centuries ago. The coming of the 20th Century, as well as two World Wars, lead to several innovations and the production of Chloroquine. Eventually, Hydroxychloroquine was synthesized in the 1950s and has seen continued use since then. There have been plenty of health properties related to Hydroxychloroquine, although there have been some noted toxicities.
Part II-1: Evidence as Treatment Against SARS-COV2
Here, we look at the use of Hydroxychloroquine against SARS-COV2. Along with some of the targets mentioned in Part I, I include another possible target. I then go into the evidence supporting combination therapy with Hydroxychloroquine with Zinc based on prior evidence of Hydroxychloroquine operating as an ionophore. Also, Azithromycin and Hydroxychloroquine may illicit a synergistic effect, although this is also likely to lead to a greater risk of adverse reactions.
Part II-2: Evidence as Treatment Against SARS-COV2 (Continued)
I provide one additional study that looked at all 3 therapeutics together (Hydroxychloroquine, Zinc, and Azithromycin). I then add some context to some of the meta-analyses and why it’s good to look at the studies included in such studies. Remember, therapeutics have a very specific window of effectiveness and both risks/benefits should be weighed to determine when and how much of a therapeutic is used.
Part III-1: Cardiac Arrhythmia, Media Hysteria, and Institutional Capture
Part of a paid Subscriber post, I dissect the information regarding Hydroxychloroquine’s cardiac arrhythmia concerns and see if the concerns are real or based predominately on media hysteria.
Part III-2: Cardiac Arrhythmia, Media Hysteria, and Institutional Capture (Continued)
Here, I summarize the information outlined in Part III-1 and give my perspective on Hydroxychloroquine. I also include citations for the papers I examined for the Paid Subscriber only content.
Modern Discontent is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.